Owing to the rising demand for compatible organs for transplantation purpose, 3D bioprinting has demonstrated to be a powerful technology in synthetically fabricating functional cells, tissues and organs
Humans frequently experience tissue dysfunctioning and damage; however, not in all cases, the body's tissue regeneration ability allows full recovery from the incurred injury. The conventional method of treating such trauma entails the transplantation of injured tissues or organs.
However, this is related to several drawbacks, such as the lack of compatible donors, possibility of graft rejection and post-operative problems. The other approach involves the integration of cells, growth factors and scaffolds, in order to build a three-dimensional (3D) functional tissue that imitates the human tissue; this method is less efficient, takes more time and may cause non-homogeneous cell distribution in the matrix.
As a result, 3D bio printing is nowadays being explored to create intricate anatomical structures in a layer-wise form with the help of computerized technology. The technique has high precision, superior resolution, fast processing time and is economical.
Over the last two decades, the concept of 3D printing technology in healthcare sector has evolved significantly, paving its path across a myriad of applications
The current IP landscape features the presence of over 3,300 patents focused on 3D bioprinting and associated innovations. It is worth mentioning that more than 20% patents (belonging to simple families) are granted patents.
More than half of the patents (both granted patents and applications pending for approval) related to 3D bioprinting have more than 15 years of exclusivity, indicating that this is a nascent field of research. Further, the IP landscape features the presence of over 770 applicants, including established companies, as well as academic institutes.
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The current IP landscape of 3D bioprinting is distributed across several innovation categories, featuring various focus areas of the patents
It is worth mentioning that the innovation area of close to 80% of the patents is centrally aligned to the scope of report whereas 20% of the patents are focused in the innovation areas which are peripheral to the scope of project. Additionally, around 40% of the patents were focused on innovations featuring different 3D bioprinted materials, followed by patents focusing on technological advances in 3D bioprinting (17%).
Prior art searches are useful in understanding the contemporary state of art in a specific field of research and developing an idea on the scope of likely future developments
The most frequently used words / phrases in the titles of patents in the 3D bioprinting dataset were identified; majority (21%) of the patents include the word method in their titles, followed by print (15%) and tissue (8%).
Further, most of the patents featuring the word method were filed within the US, indicating a lot of active 3D bioprinting research being conducted in this region. Further, the IP literature featuring the word print was focused on printing different living tissues, organs and biomedical parts.
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More than 60 IP publications emerged as the most valuable documents, covering some of the recent innovations in the 3D bioprinting domain
The value of patent not only resides within the time it must expire, but also depends on several other parameters, that determine whether the patent is of a greater importance or not. The more value a patent application acquires, corresponds to it being more novel and technically advanced in the domain. An approximate valuation of patent must generally consider both qualitative and quantitative aspects of the IP documents being analyzed.
Majority (75%) of the IP documents in the 3D bioprinting domain are patent applications (of these, around 2% are ranked amongst highly valued innovations). Further, most of the rank 1 granted patents / applications have more than 15 years till expiry.
The presence of low number of active patents in this domain enables the innovators to freely explore and operate in different innovations areas
Given the fact that a large number of IP documents are filed / published every year, in a singular field of innovation, it is important for innovators to identify relevant innovation foci. This helps define prevalent R&D trends and thereby, direct future research efforts, patenting activity and eventually, product development and launch.
Based on our proprietary method, more than 50% of the sub-categories have high freedom to operate (owing to the less number of active patents as compared with total number of patents filed in this domain), whereas 35% of the subcategories have moderate freedom to operate.
cooperative patent classification (CPC), an extension of International Patent Classification (IPC) System, is an elaborate system of codes designed to organize the key aspects of inventions
We identified 10 CPC families as key pockets of innovation; interestingly, the most frequently mentioned family in the dataset is related to method of manufacturing 3D bioprinting. Further, majority (22%) of the patents belong to A61 CPC family, followed by patents belonging to C12N family (16%).
White spaces are considered to be the areas in the patent landscape (with little / no patenting activity) that has the ability to attain exclusivity in future
Based on the white space analysis, the emerging areas of innovation within the 3D bioprinting domain were identified, focusing on different 3D bioprinting systems.
Presently, majority of innovation are observed to be focused on different methods of bioprinting and application of 3D bioprinting process. However, various areas, such as bioprinting using machine learning, bioprinting of cell / cellular structure and composition of bioprinting material were identified as potential white spaces.
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New Jordan 2020, If recent releases are any indication, the Air Jordan 1 Zoom CMFT seems to be generating more interest than it did a year ago. With the release of its latest colorway, seemingly inspired by CO.JP "Metallic Silver", the silhouette adds to an exciting list of upcoming silhouettes. Unlike previous Japanese limited editions, this pair of uppers is made entirely of suede. However, the shade of grey itself is very similar to its inspiration, albeit without the metallic finish. However, the Swoosh and collar don't have this sheen, and they have a darker, more silver-like appearance. Elsewhere, white neutrals are used to accentuate the midsole, while deep blacks are used to accentuate Wings and various brands.
2020 Cheap Jordans, Due to the influx of colorways over the past few years, Nike is about to completely run out of Dunk High and Low colorways. However, with new spinoffs like the Dunk High Up, the brand is trying to breathe new life into the iconic style. The bright colors used here add variety and are suitable as a celebration of the upcoming festival. A darker shade of orange than "Syracuse" comes in shaggy suede covered in gold or bright green paint and panels. By the way of the eyes, a soft red pastel takes center stage, and is tied with a purple cord that echoes the side Swoosh. Also, while the design may appear too busy on specs, the white base and midsole help balance the color palette.
Retro Jordan 2021, the Air Jordan 1 has rarely staged the show. That's what the AJ1 Mid and Zoom CMFT have evolved into. With its latest iteration, however, the high-top appears to be reprising that role, wearing an anodized finish almost entirely. For starters, anodizing is a process that uses electrochemical reactions to effectively improve the durability and corrosion resistance of metal surfaces. Also, it is used for decorative purposes as the color can be adjusted to a certain extent. The bright blue, almost green gradient of the upper is just one possibility, and its metallic sheen makes it look even more real. However, the immersion is broken when the Swoosh, laces and tread are all matte black.
New Jordan 2020, If 1971 was the time when the Nike brand was officially launched, then in 1982, the Air Force 1 was also released. That was only 11 years later, and the Air Force 1 was one of the company's first product lines. The Nike Air Force 1 was launched by then Nike designer Bruce Kilgore as a basketball player's line of shoes. Of course, the product at the time was very successful. Following the introduction of sneakers such as "London" and "Paris", Nike has launched another design for the 40th anniversary, the Air Force 1 Mid "Berlin".
2020 Cheap Jordans, Similar to its predecessor, the upcoming design will subtly pay homage to the German capital through its colour scheme and brand accents. Since Berlin is informally known as the "Grey City", with granite finishes for most of its buildings and famous for its cloudy skies in autumn and winter, the shoe will feature "Cave" on the leather upper and midsole. Stone" finish shade. The bold black on the laces and suede overlay represents the black bear on the city flag and the famous nightlife, while the white features the Nike Swoosh logo on the cheekbones, shoes, heel tab and tongue. Finally, the metal laces at the eyelets will be stylized as the city logo, and the teal embroidered area code "030" will help complete the overall aesthetic of the sporty version. the sport.
Retro Jordan 2021, It is said that in order to match the previously revealed "Bred" colorway, Jordan Brand's Air Jordan 1 LV8D Eleised will also be available in "Wolf Grey" and "Onyx" two colors. Also available in a two-tone design, the latest version features the classic women's Air Jordan 1 with a clean white leather upper with contrasting overlays and toe cap. Other details of the shoe include embroidered wings on the back, and a nubuck midsole. Completing the shoe's design is a chunky white midsole and an enlarged contrasting rubber outsole. The sneaker features a white leather upper with a tan leather overlay that gives the sneaker a unique two-tone look. The Air Jordan brand is minimalist with a single Jumpman on the heel of the midsole, no tongue tab, and a silhouette of the Wings logo stitched on the sole. The sneaker's standout feature is an exaggerated white midsole and tan outsole that complement the shoe.
jordan shoes 2019, In addition to the Air Jordan 1 LV8D Eleised Onyx, Jordan Brand will also release the Air Jordan 1 LV8D Eleised Wolf Grey. Here is its official picture. Designed for women, the Air Jordan 1 LV8D Eleised features a chunky sole for a taller look. This shoe features a white and grey leather upper with a perforated toe cap and an embroidered Wings logo on the heel. Other details include a cork footbed, white midsole, and grey and tan rubber outsole.
New Jordan 2020, The upcoming LeBron x Nike Dunk Low “Fruity Pebbles,” whether part of an ongoing product relationship or celebrating again an athlete's favorite cereal, joins a collection that was essentially built by the LeBron 4 back in 2006. Compared to the PE and LeBron 19 Low that launched earlier this month, this Dunk is more acceptable. The pebbles only appear on the laces and graphic-covering insoles, not the soles or insoles, which are decorated with grain. Beyond that, the overlays are a solid bright red, blue and muted yellow marking adjacent sections: the latter above the collar, the former across the Swoosh, lining and LeBron-branded heel tab. White neutrals are used throughout the shoe, including the sole, tongue and midsole.
2020 Cheap Jordans, Over the past three years, the Air Jordan 1 Mid has become a wildly popular style. And, while the NIKE, Inc. behemoth continues to produce adult-sized designs, it hasn't forgotten about the youth. The mid-top trim from Michael Jordan's first signature sneaker recently appeared in a spring outfit full of clever embellishments. First, the dominant "white" color palette of the top and sole units lets shades of green, red and orange shine. The Jordan 1 silhouette's quarter, heel and ankle overlays include classic stitching and colorful knit reinforcement; the padding around the collar also features knit construction, adding a modern twist to Peter Moore's 37-year-old design. To complete the "handcrafted" look, the retro version incorporates a whimsical bead that reads "JORDAN" on the bottom of the tongue.
Retro Jordan 2021, Released in 1994, the Reebok Kamikaze is considered one of the most important shoes in basketball shoe history. Pioneering the competitive basketball shoe market, the Reebok Kamikaze was the first signature shoe of Seattle SuperSonics "ruler" Sean Kemp, joining a lineup featuring Shaquille O'Neal's Shaqnosis line, followed by Allen Iverson's answer line. Today, Reebok revealed that Kamikaze has changed its name to Hurrikaze. Japan popularized the term "kamikaze" during World War II, when pilots almost risked their lives to use planes as missiles. Later, the term will be used to denote activities that have a large impact at a high cost. Sean Kemp, known for his powerful dunks and slam attacking the rim, eventually earned the nickname.
jordan shoes 2019, "As a brand, we have a responsibility to be accountable, to learn and to grow, and while we can't undo the past, we can certainly influence change in the future," said Portia Blunt, vice president and executive officer of Reebok Global Apparel, who leads its Human Rights Awards. "By taking this initiative, we mark progress and recognize the importance of words to the individuals we serve in the diverse global sneaker community."
New Jordan 2020, Nike has been very active since the beginning of 2022 compared to the first half of last year. From Chinese New Year to Air Max Day, the brand can't keep up with all the new arrivals they're launching. One of the duos, Dunk Low "Setsubun," unfortunately got lost in the shuffle, missing the eponymous music festival for nearly a month. However, that did not delay the release of the colorway, as newly leaked official photos suggest there will be one soon. Setsubun, which translates to "sector of the season", is a celebration celebrated in early February. According to the Japanese lunar calendar, the festival is held the day before the beginning of spring. While Halloween is not a national holiday, many people still do rituals to drive away bad moods. Jifen, also known as the "Bean Throwing Festival," is best commemorated with additional graphics on the shoes. For example, the great horn master Tsuno Daishi has purple thread embroidered on the heel, while Swooshes replace his horns. Although the character's appearance may seem sinister, it does protect against evil and disease. Elsewhere, the imagery beneath the insole is inspired by the work of Edo-era artist Utagawa Kuniyoshi, whose vibrant colors depict the folk hero urn in action.
2020 Cheap Jordans, With countless variations, Nike is ready to deliver the Air Force 1 in its purest form, complemented by some trusted design strategies. In celebration of the Air Force 1's 40th anniversary, the shoe will be available in an official Vintage Edition, with sail and coconut cream to convey the old look we've identified decades ago. Nike kept some of the original elements, such as the silver-grey Swoosh and sole, as well as the tongue tab, while the midplate tried to replicate the nylon used in the original. To support its case, leather with a damaged finish embellishes the heel guard and stripes. With the Air Force 1 celebrating its 40th anniversary in 2022, we would have expected some collaborations with designers and stores. However, we haven't heard of any such move so far, but an influx of "GR" styles that will guarantee everyone has enough Air Force 1s.
Retro Jordan 2021, Even the limited edition can't beat the "Triple White" Air Force 1, arguably one of the most iconic pieces in the Nike collection. And, while the brand may be experimenting with unusual creative makeup for the 40th anniversary, most will probably stick to a more direct approach. The next pair, slightly modified from its neutral-dominant counterpart, is just that, offering an option for those who want something new but not too different. The shoes are almost entirely white, like they've been done a few times before. As usual, smooth leather wraps the toe, mid-panel and heel with matching laces, eye guards and tongue in between. While the sole mostly matches, the tread is darker to the touch, and the grey tones are also shown along the Swoosh, heel tab and associated branding.
jordan shoes 2019, Nike has yet to kick off the Air Force 1's 40th anniversary, as they're clearly preoccupied with Air Max Day. That hasn't stopped the company from announcing commemorative items, which include collaborations with Stussy, Civilist Berlin, and most likely Drake. Many other GRs are on the way, and more are being released every day, like this cannabis-made shade. Unlike what we're used to seeing, the silhouette looks handcrafted. The top is braided with a wide white thread that wraps everything from the toe. Even the construction of the Swoosh and heel tabs are similar, but they are colored in bright orange and blue, respectively. The bright green tongue is noticeably more typical, while the lower part of the sole is recycled, as can be seen from the faint spots.