Owing to the rising demand for compatible organs for transplantation purpose, 3D bioprinting has demonstrated to be a powerful technology in synthetically fabricating functional cells, tissues and organs
Humans frequently experience tissue dysfunctioning and damage; however, not in all cases, the body's tissue regeneration ability allows full recovery from the incurred injury. The conventional method of treating such trauma entails the transplantation of injured tissues or organs.
However, this is related to several drawbacks, such as the lack of compatible donors, possibility of graft rejection and post-operative problems. The other approach involves the integration of cells, growth factors and scaffolds, in order to build a three-dimensional (3D) functional tissue that imitates the human tissue; this method is less efficient, takes more time and may cause non-homogeneous cell distribution in the matrix.
As a result, 3D bio printing is nowadays being explored to create intricate anatomical structures in a layer-wise form with the help of computerized technology. The technique has high precision, superior resolution, fast processing time and is economical.
Over the last two decades, the concept of 3D printing technology in healthcare sector has evolved significantly, paving its path across a myriad of applications
The current IP landscape features the presence of over 3,300 patents focused on 3D bioprinting and associated innovations. It is worth mentioning that more than 20% patents (belonging to simple families) are granted patents.
More than half of the patents (both granted patents and applications pending for approval) related to 3D bioprinting have more than 15 years of exclusivity, indicating that this is a nascent field of research. Further, the IP landscape features the presence of over 770 applicants, including established companies, as well as academic institutes.
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The current IP landscape of 3D bioprinting is distributed across several innovation categories, featuring various focus areas of the patents
It is worth mentioning that the innovation area of close to 80% of the patents is centrally aligned to the scope of report whereas 20% of the patents are focused in the innovation areas which are peripheral to the scope of project. Additionally, around 40% of the patents were focused on innovations featuring different 3D bioprinted materials, followed by patents focusing on technological advances in 3D bioprinting (17%).
Prior art searches are useful in understanding the contemporary state of art in a specific field of research and developing an idea on the scope of likely future developments
The most frequently used words / phrases in the titles of patents in the 3D bioprinting dataset were identified; majority (21%) of the patents include the word method in their titles, followed by print (15%) and tissue (8%).
Further, most of the patents featuring the word method were filed within the US, indicating a lot of active 3D bioprinting research being conducted in this region. Further, the IP literature featuring the word print was focused on printing different living tissues, organs and biomedical parts.
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More than 60 IP publications emerged as the most valuable documents, covering some of the recent innovations in the 3D bioprinting domain
The value of patent not only resides within the time it must expire, but also depends on several other parameters, that determine whether the patent is of a greater importance or not. The more value a patent application acquires, corresponds to it being more novel and technically advanced in the domain. An approximate valuation of patent must generally consider both qualitative and quantitative aspects of the IP documents being analyzed.
Majority (75%) of the IP documents in the 3D bioprinting domain are patent applications (of these, around 2% are ranked amongst highly valued innovations). Further, most of the rank 1 granted patents / applications have more than 15 years till expiry.
The presence of low number of active patents in this domain enables the innovators to freely explore and operate in different innovations areas
Given the fact that a large number of IP documents are filed / published every year, in a singular field of innovation, it is important for innovators to identify relevant innovation foci. This helps define prevalent R&D trends and thereby, direct future research efforts, patenting activity and eventually, product development and launch.
Based on our proprietary method, more than 50% of the sub-categories have high freedom to operate (owing to the less number of active patents as compared with total number of patents filed in this domain), whereas 35% of the subcategories have moderate freedom to operate.
cooperative patent classification (CPC), an extension of International Patent Classification (IPC) System, is an elaborate system of codes designed to organize the key aspects of inventions
We identified 10 CPC families as key pockets of innovation; interestingly, the most frequently mentioned family in the dataset is related to method of manufacturing 3D bioprinting. Further, majority (22%) of the patents belong to A61 CPC family, followed by patents belonging to C12N family (16%).
White spaces are considered to be the areas in the patent landscape (with little / no patenting activity) that has the ability to attain exclusivity in future
Based on the white space analysis, the emerging areas of innovation within the 3D bioprinting domain were identified, focusing on different 3D bioprinting systems.
Presently, majority of innovation are observed to be focused on different methods of bioprinting and application of 3D bioprinting process. However, various areas, such as bioprinting using machine learning, bioprinting of cell / cellular structure and composition of bioprinting material were identified as potential white spaces.
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Günstig Trikots Fußball Kinder, Laut Fabrizio Romano ist Barcelona sehr an Aston Villa-Star Carney Chukwuemeka interessiert. Der Brite, der kurz vor dem letzten Vertragsjahr steht, gilt als Spieler mit großem Potenzial und könnte von der FIFA für das Training im Januar-Transferfenster bezahlt werden. Chukwuemeka wurde in Österreich als Sohn nigerianischer Eltern geboren, vertritt England aber auf U19-Ebene. Er machte seine ersten Schritte im Fußball in Northampton Town, bevor er 2016 zu Villa wechselte und 2021 sein Debüt in der Premier League gab. Seitdem hat der Mittelfeldspieler insgesamt 16 Spiele für die erste Mannschaft bestritten. Das finanziell angeschlagene Barcelona ist bestrebt, den Jugendmarkt zu nutzen, um seinen Kader in den kommenden Spielzeiten zu stärken, und Spieler wie Chukvimeka werden von großem Interesse sein. Xavi Hernandez hat auch seine Bereitschaft gezeigt, Spielern, die er seiner Meinung nach verdient, Chancen und Minuten zu geben.
Italien Trikots, Laut Marca drängen zwei lateinamerikanische Vereine darauf, den Free Agent Dani Alves zu verpflichten, nachdem sein Vertrag mit Barcelona Ende Juni ausgelaufen ist. Der mexikanische Klub Club America hat dem Brasilianer einen Deal über 3 Millionen Dollar pro Saison angeboten, um nach Mexiko-Stadt zu kommen, ein Deal, der den 39-jährigen Rechtsverteidiger zum vierthöchstbezahlten Spieler in La Liga machen würde. Auch Brasiliens Atlético Paraná interessiert sich für ihn. Alves – der Spieler mit den meisten Auszeichnungen in der Geschichte des Fußballs – ist bestrebt, einen Verein zu finden, der ihm helfen kann, ein gutes Wettbewerbsniveau aufrechtzuerhalten und sich bei der bevorstehenden Weltmeisterschaft in Katar einen Platz in der brasilianischen Nationalmannschaft zu sichern. Er hat bisher 125 Auftritte.
Fußballtrikots für Kinder, Alves hofft, dass es bei Barcelona sein wird, nur wenn der katalanische Klub beschließt, den Sechsmonatsvertrag, den er unterzeichnet hat, als er letzten Winter aus Sao Paulo zum Klub zurückkehrte, nicht zu verlängern. In der Rückrunde der Saison 2021/22 bestritt er 15 Spiele für Barcelona und steuerte dabei 1 Tor und 3 Vorlagen bei. „Ich bin nicht traurig gegangen“, sagte Alves dem Guardian. "Ich bin sehr glücklich, wieder in Barcelona zu sein. Ich habe von fünf Jahren geträumt und möchte in diesem Moment leben. Das einzige, was mir nicht gefallen hat, war, wie mein Abgang gehandhabt wurde. "Seit ich hier bin, Das habe ich ganz klar gesagt. Als 20-Jähriger möchte ich, dass die Dinge positiv angegangen werden und nichts zurückhalten. Aber der Klub hat in den letzten Jahren Verbrechen begangen. Barcelona kümmert sich nicht darum, wer für den Verein Geschichte schreibt. Als Spieler wünsche ich mir, dass Barcelona die Dinge anders macht. „Ich spreche nicht von mir, weil meine Situation eine andere ist. Ich bin Xavi [Hernandez] und dem Präsidenten für immer dankbar, dass sie mich zurückgebracht haben. Unglaublich nachdenklicher junger Mann. Aber es muss die Offsite-Arbeit verbessern. Diese Mentalität ist das genaue Gegenteil von dem, was wir vor ein paar Jahren etabliert haben: „Alles, was auf dem Platz passiert, spiegelt das wider, was draußen passiert kollektives Spiel. Und das wurde im Club ignoriert.
jordan shoes 2019, We are at the beginning of a new week, and we are already looking ahead to the content of week 50! This week is full of releases, suitable for everyone. There are also many sneakers that cannot be scored by everyone because of the limited edition. This week, Adidas and Nike launched cool shoes. Of course, we list the sales points of each pair of sports shoes so that you have the best chance of getting a pair.
We started this week with Nike SB Dunk Low Fog Black. The upper of these shoes is made of raw black suede, and the laces, tongue and lining are also black. In sharp contrast to the black upper, the swoosh is made of gray leather. Because of the use of colors, this one is really popular. The outsole is made of rubber, which completes this pair of shoes. Air Jordan 1 Mid SE "Grey Green" uses white with green and gray colors. This mid-top Air Jordan 1 has white leather upper and gray suede for the outer cover. The green is reflected in the swoosh, collar, jumpman logo and rubber outsole. The white midsole completes this pair of shoes. This new Yeezy 500 "Clay Brown" has a variety of earth tones. With this pair, the contrast is not in the use of colors, but in the materials they use. The material is composed of mesh, leather, rubber, and suede, the latter being most prominent in the faded light tones.
Nike Air Huarache LE Slate Shadow" appeared in a superb color scheme. Both the outsole and midsole are black, which is also reflected in the tongue and heel. The upper is a combination of shaded grey suede and blue neoprene. The Huarache logo on the tongue and the Nike logo on the heel also use the same blue hue. This is not just the release of a dunk, it is also the next natural decline. According to Nike, it is a classic and is now made of at least 20% recyclable materials with minimal impact on the environment while maintaining original integrity. . Nike Dunk Low White "Move to Zero" uses white canvas fabric.
The Latest Air Jordan 1 High OG Hand Crafted uses the "Black/Archaeo Brown-Dark Chocolate" color scheme and a special color matching design. This sneaker uses a variety of high-quality materials such as suede and leather. Finally, black and orange laces, white midsole and black rubber outsole complete the vibrant design.
In the New Jordan 2020, Nike Umbrellas have gradually launched their Lunar New Year products. Moreover, unlike the Air Jordan 1 Low OG and Air Jordan 1 Low OG, which both visually interpret the meaning of the "Year of the Tiger", the newly launched Blazer Mid takes "invisible, invisible, infinite" as the theme and draws inspiration from craftsmanship. Like Air Force 1, the back of the Blazer Mid is decorated with three jade stones, and their unique shapes are likely to represent the above three themes. In addition, the quilted upper has its own trio of gray, pink and blue. The bright red Swooshes and the words "Nike" on the side and heel labels respectively create an auspicious atmosphere, while also complementing the extra lace around the collar.
2020 Cheap Jordans, Nike Air Force 1 was born in 1982, and it has just passed 39 years. In the sneaker village, there are not many shoes that can retain heat for decades like the Nike Air Force 1, and even shoes of other brands are only a few. In fact, the current hot trend is shoes like NMD or MLB Boston, but no one can be sure whether these shoes will be as popular as Nike Air Force 1. To celebrate the 40th anniversary of Bruce Kilgore's iconic Air Force 1, Nike released a series of limited edition sneakers. The first version to be unveiled will be the Nike Air Force 1 Mid shoe dedicated to Paris, the city of love.
Retro Jordan 2021, The Nike Air Force 1 Mid "Paris" will be made of cream suede with a light yellow overlay. The Nike Swoosh logo on the side of the shoe, the heel loop and the tongue are embellished in blue and green. The pattern is related to the city street signs, and the number "75" is the characteristic. The embroidery on the forefoot part will match the city's zip code. Next, the metal eyelets are an homage to the iconic streets of Paris. Take a closer look, the triangular hole at the toe-may refer to the Louvre. Finally, the combination of cream midsole and yellow outsole will help complete the overall appearance of this pair of sneakers.
New Jordan Release, Jordan Brand is one of the world's leading sportswear brands. Air Jordan 1 is famous for its extremely fashionable, eye-catching and creative design, and has always been enthusiastically loved by fans. Especially the Air Jordan 1 High shoe series, which is extremely easy to use and not fussy about users. It is one of Jordan Brand's best-selling shoe series. One of the latest editions of Jordan Brand will be an exclusive women's version of the Air Jordan 1 Low called "Marina Blue". The coveted design has recently been renewed in a crater style through the use of recycled materials. The Nike Dunk Low named "Dark Marina Blue" will mainly be covered in navy tones, and the toe and reeds will appear in this vivid tone. Leather covering. Next, like the Dunk Low "Kentucky" version, the blue tone will continue to highlight the Nike Swoosh logo on the side of the shoe, the tongue border, the Jumpman logo, and the found number "23" and other details. The laces are fixed. Finally, the combination of white midsole and blue outsole will help complete the overall appearance of this pair of sneakers.
After multiple delays, the Air Jordan 9 Chile Red Black is finally set to release on February 25th. Primarily in ruby tones, this upcoming retro version draws comparisons to the Air Jordan "Motorboat Jones" colorway that debuted in December 2012 as part of the Air Jordan "Kilroy Pack," a collection of six sneakers inspired by From a different self Michael Jordan was adopted after he retired from the NBA for the first time. Compared to its "Challenge Red" predecessor, the "Chile Red" version features a more prominent scarlet hue throughout the upper, and even features patent leather above the midsole. The outsole, lace loops, and heel detail feature a contrasting "black" color, a nod to the Chicago Bulls team color.
The Air Jordan 4 was the first sneaker to be released in the U.S. market. It's also the first time a shoe from Spike Lee's "Do the Right Thing" has moved beyond basketball to have a major impact on contemporary pop culture. All eyes were on Jordan and his path to the top. The Air Jordan 4 is having a very interesting season in 2021, with numerous retro versions of the popular "Lightning" colorway, Union LA collaborations, and popular GR versions like the "Tech White" variant. However, it looks like this Tinker-designed shoe line will continue to expand further in 2022 with more releases, one of which is this Air Jordan 4 “Infrared 23.”
Retro Jordan 2021, The upper of this shoe is mostly covered in shades of gray, which allows its standard color block to stand out openly. Most of the shoe will be finished in a "dark grey" nubuck fabric, while the black accent will appear on the cage, mesh, laces, lining and heel. Next, the "Cement Grey" colorway will feature the Jumpman logo on the forefoot and heel, while the "Infrared 23" will feature the Jumpman logo on the eyelet and tongue. Finally, the midsole section will be designed in a black/white tone, superimposed on the grey outsole.
jordan shoes 2019, Towards the end of 2020, Nike kicked off a campaign earlier this year to re-launch true OG Jordans in colorways including Varsity Red or Neutral Grey. And this 2021, the fall retro collection will feature classic Jordan Brand designs such as the Air Jordan 1, Air Jordan 4 or Air Jordan 5. And just recently, Jordan Brand is currently preparing to launch a new Air Jordan 1 LV8D Eleised design. This exclusive women's shoe reimagines the AJ1 Low with a thick sole for a loafer look. Typically, Nike shoes are designed with a platform that is highly similar to its height. Alongside the Air Jordan 1 Low LV8D, so is Jordan Brand's offering, a new shoe that adds height to the beloved classic. Unlike the off-white version that launched earlier this week, this colorway is more traditionally inspired, featuring the legendary "Bred" colorway. The use of black and red is similar to previous years, and the outfit features a low-top, minimalist Wings logo and a brand-removed tongue. Below, the tool's impact is also relatively realistic, although only in the midsole to provide a tint to the height of the design.