Owing to the rising demand for compatible organs for transplantation purpose, 3D bioprinting has demonstrated to be a powerful technology in synthetically fabricating functional cells, tissues and organs
Humans frequently experience tissue dysfunctioning and damage; however, not in all cases, the body's tissue regeneration ability allows full recovery from the incurred injury. The conventional method of treating such trauma entails the transplantation of injured tissues or organs.
However, this is related to several drawbacks, such as the lack of compatible donors, possibility of graft rejection and post-operative problems. The other approach involves the integration of cells, growth factors and scaffolds, in order to build a three-dimensional (3D) functional tissue that imitates the human tissue; this method is less efficient, takes more time and may cause non-homogeneous cell distribution in the matrix.
As a result, 3D bio printing is nowadays being explored to create intricate anatomical structures in a layer-wise form with the help of computerized technology. The technique has high precision, superior resolution, fast processing time and is economical.
Over the last two decades, the concept of 3D printing technology in healthcare sector has evolved significantly, paving its path across a myriad of applications
The current IP landscape features the presence of over 3,300 patents focused on 3D bioprinting and associated innovations. It is worth mentioning that more than 20% patents (belonging to simple families) are granted patents.
More than half of the patents (both granted patents and applications pending for approval) related to 3D bioprinting have more than 15 years of exclusivity, indicating that this is a nascent field of research. Further, the IP landscape features the presence of over 770 applicants, including established companies, as well as academic institutes.
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The current IP landscape of 3D bioprinting is distributed across several innovation categories, featuring various focus areas of the patents
It is worth mentioning that the innovation area of close to 80% of the patents is centrally aligned to the scope of report whereas 20% of the patents are focused in the innovation areas which are peripheral to the scope of project. Additionally, around 40% of the patents were focused on innovations featuring different 3D bioprinted materials, followed by patents focusing on technological advances in 3D bioprinting (17%).
Prior art searches are useful in understanding the contemporary state of art in a specific field of research and developing an idea on the scope of likely future developments
The most frequently used words / phrases in the titles of patents in the 3D bioprinting dataset were identified; majority (21%) of the patents include the word method in their titles, followed by print (15%) and tissue (8%).
Further, most of the patents featuring the word method were filed within the US, indicating a lot of active 3D bioprinting research being conducted in this region. Further, the IP literature featuring the word print was focused on printing different living tissues, organs and biomedical parts.
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More than 60 IP publications emerged as the most valuable documents, covering some of the recent innovations in the 3D bioprinting domain
The value of patent not only resides within the time it must expire, but also depends on several other parameters, that determine whether the patent is of a greater importance or not. The more value a patent application acquires, corresponds to it being more novel and technically advanced in the domain. An approximate valuation of patent must generally consider both qualitative and quantitative aspects of the IP documents being analyzed.
Majority (75%) of the IP documents in the 3D bioprinting domain are patent applications (of these, around 2% are ranked amongst highly valued innovations). Further, most of the rank 1 granted patents / applications have more than 15 years till expiry.
The presence of low number of active patents in this domain enables the innovators to freely explore and operate in different innovations areas
Given the fact that a large number of IP documents are filed / published every year, in a singular field of innovation, it is important for innovators to identify relevant innovation foci. This helps define prevalent R&D trends and thereby, direct future research efforts, patenting activity and eventually, product development and launch.
Based on our proprietary method, more than 50% of the sub-categories have high freedom to operate (owing to the less number of active patents as compared with total number of patents filed in this domain), whereas 35% of the subcategories have moderate freedom to operate.
cooperative patent classification (CPC), an extension of International Patent Classification (IPC) System, is an elaborate system of codes designed to organize the key aspects of inventions
We identified 10 CPC families as key pockets of innovation; interestingly, the most frequently mentioned family in the dataset is related to method of manufacturing 3D bioprinting. Further, majority (22%) of the patents belong to A61 CPC family, followed by patents belonging to C12N family (16%).
White spaces are considered to be the areas in the patent landscape (with little / no patenting activity) that has the ability to attain exclusivity in future
Based on the white space analysis, the emerging areas of innovation within the 3D bioprinting domain were identified, focusing on different 3D bioprinting systems.
Presently, majority of innovation are observed to be focused on different methods of bioprinting and application of 3D bioprinting process. However, various areas, such as bioprinting using machine learning, bioprinting of cell / cellular structure and composition of bioprinting material were identified as potential white spaces.
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jordan shoes 2019, We are at the beginning of a new week, and we are already looking ahead to the content of week 50! This week is full of releases, suitable for everyone. There are also many sneakers that cannot be scored by everyone because of the limited edition. This week, Adidas and Nike launched cool shoes. Of course, we list the sales points of each pair of sports shoes so that you have the best chance of getting a pair.
We started this week with Nike SB Dunk Low Fog Black. The upper of these shoes is made of raw black suede, and the laces, tongue and lining are also black. In sharp contrast to the black upper, the swoosh is made of gray leather. Because of the use of colors, this one is really popular. The outsole is made of rubber, which completes this pair of shoes. Air Jordan 1 Mid SE "Grey Green" uses white with green and gray colors. This mid-top Air Jordan 1 has white leather upper and gray suede for the outer cover. The green is reflected in the swoosh, collar, jumpman logo and rubber outsole. The white midsole completes this pair of shoes. This new Yeezy 500 "Clay Brown" has a variety of earth tones. With this pair, the contrast is not in the use of colors, but in the materials they use. The material is composed of mesh, leather, rubber, and suede, the latter being most prominent in the faded light tones.
Nike Air Huarache LE Slate Shadow" appeared in a superb color scheme. Both the outsole and midsole are black, which is also reflected in the tongue and heel. The upper is a combination of shaded grey suede and blue neoprene. The Huarache logo on the tongue and the Nike logo on the heel also use the same blue hue. This is not just the release of a dunk, it is also the next natural decline. According to Nike, it is a classic and is now made of at least 20% recyclable materials with minimal impact on the environment while maintaining original integrity. . Nike Dunk Low White "Move to Zero" uses white canvas fabric.
The Latest Air Jordan 1 High OG Hand Crafted uses the "Black/Archaeo Brown-Dark Chocolate" color scheme and a special color matching design. This sneaker uses a variety of high-quality materials such as suede and leather. Finally, black and orange laces, white midsole and black rubber outsole complete the vibrant design.
New Jordan 2020, Despite the growing demand for the Air Jordan 1 Low to return to its original form and style, lifestyle-focused styles continue to be experimented with, most recently appearing in the "Iron Ore" assortment. Similar to the mid-top rendition of Michael Jordan's first signature sneaker seen earlier, the upcoming model features a grayscale pattern on its leather and textile upper. The overlays around the toe, tongue and heel are made from solid grey supple leather, while the padding in these same areas (plus the tongue) is made of heather-patterned woven cotton. While the sleek design isn't new to the Air Jordan 1 collection, its pairing with pale pink laces is a novel option from the NIKE, Inc. team. Despite the low-top's lack of series branding, Jordan Brand may have prepared other models in its lineup with a similar "iron gray" finish and light rose color for spring and summer releases.
Although 2020 Cheap Jordans has yet to announce an official collection for Valentine's Day 2022, several of its sneakers have recently appeared in Valentine's-themed colorways. For example, consider the recent arrival of the Nike Air Max 95 in black, grey and red. Like the previous stealth iteration of Sergio Lozano's 1995 design, the upcoming sneaker completely covers its leather, mesh, and nubuck upper, in a lacquered black tone that lets the supportive hue take center stage. Iron-grey-inspired lace loops break up the near-uniform look, but their boldness pales in comparison to the branding on the top of the tongue and side heel. The "airmax" text on the tongue retains its standard design, but the swoosh logo on the sidewall features a three-dimensional "gem" construction similar to that seen on many of the Air Force 1 Mid's recent pairs. Down below, the visible airbag and "NIKE AIR" branding on the outsole are also in a ruby tone, while the foam that comes with the midsole is a muted grey. Still, all of the above colors help create a unique option for any Valentine's Day plan.
jordan shoes 2019, Nike doesn't seem to be relying too much on spring-related hues this year. While pastels have been seen on multiple pairs of shoes in recent months, it's nowhere near the level of previous years. The same goes for the brand's latest GR Dunk Low, as the colorway is only available in a tinge of light blue. This cool shade is limited to the collar, with a suede edge in a shade reminiscent of the beloved "college blue." An adjacent dark purple hue is used to accentuate the Swoosh and heel embroidery, the latter featuring "NIKE" against an indigo-dyed backdrop. Elsewhere in the building, the base and cladding are off-white and grey, respectively.
In the New Jordan 2020, Nike Umbrellas have gradually launched their Lunar New Year products. Moreover, unlike the Air Jordan 1 Low OG and Air Jordan 1 Low OG, which both visually interpret the meaning of the "Year of the Tiger", the newly launched Blazer Mid takes "invisible, invisible, infinite" as the theme and draws inspiration from craftsmanship. Like Air Force 1, the back of the Blazer Mid is decorated with three jade stones, and their unique shapes are likely to represent the above three themes. In addition, the quilted upper has its own trio of gray, pink and blue. The bright red Swooshes and the words "Nike" on the side and heel labels respectively create an auspicious atmosphere, while also complementing the extra lace around the collar.
2020 Cheap Jordans, Nike Air Force 1 was born in 1982, and it has just passed 39 years. In the sneaker village, there are not many shoes that can retain heat for decades like the Nike Air Force 1, and even shoes of other brands are only a few. In fact, the current hot trend is shoes like NMD or MLB Boston, but no one can be sure whether these shoes will be as popular as Nike Air Force 1. To celebrate the 40th anniversary of Bruce Kilgore's iconic Air Force 1, Nike released a series of limited edition sneakers. The first version to be unveiled will be the Nike Air Force 1 Mid shoe dedicated to Paris, the city of love.
Retro Jordan 2021, The Nike Air Force 1 Mid "Paris" will be made of cream suede with a light yellow overlay. The Nike Swoosh logo on the side of the shoe, the heel loop and the tongue are embellished in blue and green. The pattern is related to the city street signs, and the number "75" is the characteristic. The embroidery on the forefoot part will match the city's zip code. Next, the metal eyelets are an homage to the iconic streets of Paris. Take a closer look, the triangular hole at the toe-may refer to the Louvre. Finally, the combination of cream midsole and yellow outsole will help complete the overall appearance of this pair of sneakers.
New Jordan Release, Jordan Brand is one of the world's leading sportswear brands. Air Jordan 1 is famous for its extremely fashionable, eye-catching and creative design, and has always been enthusiastically loved by fans. Especially the Air Jordan 1 High shoe series, which is extremely easy to use and not fussy about users. It is one of Jordan Brand's best-selling shoe series. One of the latest editions of Jordan Brand will be an exclusive women's version of the Air Jordan 1 Low called "Marina Blue". The coveted design has recently been renewed in a crater style through the use of recycled materials. The Nike Dunk Low named "Dark Marina Blue" will mainly be covered in navy tones, and the toe and reeds will appear in this vivid tone. Leather covering. Next, like the Dunk Low "Kentucky" version, the blue tone will continue to highlight the Nike Swoosh logo on the side of the shoe, the tongue border, the Jumpman logo, and the found number "23" and other details. The laces are fixed. Finally, the combination of white midsole and blue outsole will help complete the overall appearance of this pair of sneakers.
After multiple delays, the Air Jordan 9 Chile Red Black is finally set to release on February 25th. Primarily in ruby tones, this upcoming retro version draws comparisons to the Air Jordan "Motorboat Jones" colorway that debuted in December 2012 as part of the Air Jordan "Kilroy Pack," a collection of six sneakers inspired by From a different self Michael Jordan was adopted after he retired from the NBA for the first time. Compared to its "Challenge Red" predecessor, the "Chile Red" version features a more prominent scarlet hue throughout the upper, and even features patent leather above the midsole. The outsole, lace loops, and heel detail feature a contrasting "black" color, a nod to the Chicago Bulls team color.
The Air Jordan 4 was the first sneaker to be released in the U.S. market. It's also the first time a shoe from Spike Lee's "Do the Right Thing" has moved beyond basketball to have a major impact on contemporary pop culture. All eyes were on Jordan and his path to the top. The Air Jordan 4 is having a very interesting season in 2021, with numerous retro versions of the popular "Lightning" colorway, Union LA collaborations, and popular GR versions like the "Tech White" variant. However, it looks like this Tinker-designed shoe line will continue to expand further in 2022 with more releases, one of which is this Air Jordan 4 “Infrared 23.”
Retro Jordan 2021, The upper of this shoe is mostly covered in shades of gray, which allows its standard color block to stand out openly. Most of the shoe will be finished in a "dark grey" nubuck fabric, while the black accent will appear on the cage, mesh, laces, lining and heel. Next, the "Cement Grey" colorway will feature the Jumpman logo on the forefoot and heel, while the "Infrared 23" will feature the Jumpman logo on the eyelet and tongue. Finally, the midsole section will be designed in a black/white tone, superimposed on the grey outsole.
jordan shoes 2019, Towards the end of 2020, Nike kicked off a campaign earlier this year to re-launch true OG Jordans in colorways including Varsity Red or Neutral Grey. And this 2021, the fall retro collection will feature classic Jordan Brand designs such as the Air Jordan 1, Air Jordan 4 or Air Jordan 5. And just recently, Jordan Brand is currently preparing to launch a new Air Jordan 1 LV8D Eleised design. This exclusive women's shoe reimagines the AJ1 Low with a thick sole for a loafer look. Typically, Nike shoes are designed with a platform that is highly similar to its height. Alongside the Air Jordan 1 Low LV8D, so is Jordan Brand's offering, a new shoe that adds height to the beloved classic. Unlike the off-white version that launched earlier this week, this colorway is more traditionally inspired, featuring the legendary "Bred" colorway. The use of black and red is similar to previous years, and the outfit features a low-top, minimalist Wings logo and a brand-removed tongue. Below, the tool's impact is also relatively realistic, although only in the midsole to provide a tint to the height of the design.